Effects of Grape Seed Extract in Subjects with Pre-Hypertension

This study was undertaken to determine whether grape see extracts (GSE) which contain powerful vasodilator phenolic compounds lower blood pressure (BP) in subjects with pre-hypertension. The subjects were randomized into a placebo or an experimental group (GSE at a dose of 300 mg/day) and treated for 8 weeks. Serum lipids and blood glucose were measured at the beginning of the study and at the end. BP was recorded using an ambulatory monitoring device at the start of the treatment period and at the end. Both the systolic and diastolic blood pressure were lower after treatment with GSE as compared with placebo. There were no significant changes in serum lipids or blood glucose values. These findings suggest that GSE could be used as a nutraceutical in a lifestyle modification program for patients with pre-hypertension.

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Recent Advances in Cardiovascular Disease – Effects of Grape Seed Extract in Subjects with Pre-Hypertension (PDF)

Effect of a Novel Grape Seed Extract on Blood Pressure in Subjects with Prehypertension (PDF)

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  1. Nic B. Shan 02. Apr, 2011 at 4:39 am #

    May i know why the PDF on the Effect of Novel Grape Seed Extract on Blood Pressure in Subjects with Prehypertension has removed or can no longer be found in your website?

    I would appreciate if you can send me the Full Study in PDF re Prehypertension and what reputable medical journal has been published on this.

    We are reviving our interest in positioning MegaNatural BP in prehypertensive patients.

    Your president Mr Anil Shrikhande is acquainted with me.

    Regards,
    Nic B. Shan
    JB Orchid Pharmaceuticals INC.
    Cebu, Philippines

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